While significant gains have been made to address the global burden of maternal mortality, as demonstrated by the 34.5% reduction between 2000 and 2020, 1 progress has been uneven. A disproportionate burden is evident in low-income and middle-income countries (LMICs), 1,2 particularly in the perinatal phase,3–5 a neglected yet critical period for action to prevent morbidity and mortality. This series: Maternal Health in the Perinatal Period and Beyond, jointly published in The Lancet Global Health and eClinicalMedicine, presents four papers out- lining the complex factors driving adverse health out- comes in the perinatal and later post-partum periods and strategies to address this maternal inequity.